abstract：AIM:To specify risk factors affecting development and frequency of complications early after the bypass operation in direct myocardial revascularization. MATERIAL AND METHODS:455 patients with ischemic heart disease (IHD) of whom 392 (86.2%) had stable angina pectoris class III-IV, 25 (5.5%) had unstable angina pector...

journal_title：Terapevticheskii arkhiv

authors： Chernov SA

更新日期：2002-01-01 00:00:00

abstract：AIM:To elucidate whether secretory phospholipase A2 (sPLA2) level in the blood and catalytic activity are significant predictors of restenosis after coronary angioplasty (CAP). MATERIAL AND METHODS:Samples of venous blood were obtained from 24 patients before CAP and 1, 3, 6 days and 6 months after it. sPLA2 was measu...

journal_title：Terapevticheskii arkhiv

authors： Korotaeva AA,Provatorov SI,Samoĭlova EV,Kaminnyĭ AI,Sumarokov AB,Pirkova AA,Samko AN,Prokazova NV

更新日期：2002-01-01 00:00:00

abstract：AIM:To study the relationship between clinical values of a standard epidemiological study of a male population and the length and variability of Q-T and R-R intervals. MATERIAL AND METHODS:A representative sampling from a male population (2184 subjects aged 25-64 years) in Novosibirsk was examined using standard epide...

journal_title：Terapevticheskii arkhiv

authors： Nikitin IuP,Kuznetsov AA,Maliutina SK

更新日期：2002-01-01 00:00:00

abstract：AIM:To study effects of laser therapy in combined treatment of pneumonia on external respiration function, membrane permeability, microcirculation and serum trace elements. MATERIAL AND METHODS:142 pneumonia patients were randomly divided into two groups: 96 patients treated with drugs and laser radiation (the study g...

journal_title：Terapevticheskii arkhiv

authors： Amirov NB

更新日期：2002-01-01 00:00:00

abstract：AIM:To elucidate features of hemodynamics in patients with lymphoma and hemodynamic effects of polychemotherapy. MATERIAL AND METHODS:Parameters of central hemodynamics were studied echocardiographycally in 42 patients with lymphoma. RESULTS:In a definite rise in the levels of tumor progression markers, changes in th...

journal_title：Terapevticheskii arkhiv

authors： Shevchenko IuL,Bobrov LL,Novik AA,Obrezan AG,Krysiuk OB

更新日期：2002-01-01 00:00:00

abstract：AIM:To examine structural and electrophysiological predictors of the onset and establishment as chronic of cardiac fibrillation (CF). MATERIAL AND METHODS:Echocardiography, transesophageal electrophysiological examination of the heart were performed in 420 cases of paroxysmal cardiac fibrillation (PCF). They were diag...

journal_title：Terapevticheskii arkhiv

authors： Iskenderov BG,Rakhmatullov FK

更新日期：2001-01-01 00:00:00

abstract：AIM:To quantify interleukin-8 (IL-8), interleukin-2 (IL-2) and soluble receptor of IL-2 (sIL-2r) in blood serum of patients with various forms of ischemic heart disease (IHD). MATERIAL AND METHODS:Levels of IL-8, IL-2 and sIL-2r were measured with enzyme immunoassay (EIA) in the serum of 75 patients with IHD: angina o...

journal_title：Terapevticheskii arkhiv

authors： Mazurov VI,Stvolov SV,Linetskaia NE,Baldueva IA

更新日期：2001-01-01 00:00:00

abstract：AIM:To evaluate alterations in the immune system (IS) in patients with different forms of secondary immunodeficiency and design of differentiated programs of reestablishment of defective functions depending on pathogenetically important type of deficiency of immunocompetent cells. MATERIALS AND METHODS:Clinicoimmunolo...

journal_title：Terapevticheskii arkhiv

authors： Kolesnikov AP,Khabarov AS,Kozlov VA

更新日期：2001-01-01 00:00:00

abstract：AIM:To study morphofunctional features of the upper airways (UAW) in wakeful patients (juveniles with arterial hypertension stage I) and genetic predisposition to UAW obstruction in sleeping patients. MATERIAL AND METHODS:The examination of 18 juveniles with arterial hypertension stage I and II normotensive juveniles ...

journal_title：Terapevticheskii arkhiv

authors： Voronin IM,Stegachev SK,Pokidkin AV,Temartseva TP,Belov AM,Chuchalin AG

更新日期：2001-01-01 00:00:00

abstract：AIM:To study clinical features of bronchial asthma (BA) associated with internal picture and nosogenic reactions. MATERIAL AND METHODS:Clinical features of BA were studied in 108 patients (38 males and 70 females, mean age 44.7 +/- 1.4 years, mean BA duration 6.6 +/- 0.76 years) treated in the clinic of the I. M. Sech...

journal_title：Terapevticheskii arkhiv

authors： Ovcharenko SI,Smulevich AB,Drobizhev MIu,Ishchenko EN,Bevz IA

更新日期：2001-01-01 00:00:00

abstract：AIM:To study generation of active oxygen forms in the whole blood of patients with chronic bronchitis and correction of the detected disorders. MATERIAL AND METHODS:By means of registration of spontaneous and staphylococcus-induced luminol-dependent chemiluminescence (LDCL) of the whole blood, generation of active oxy...

journal_title：Terapevticheskii arkhiv

authors： Abdrakhmanova LM,Farkhutdinov UR,Farkhutdinov RR

更新日期：2001-01-01 00:00:00

abstract：AIM:To specify circulatory disorders in the bed of common carotid artery (CCA) in hypertensive patients and these disorders influence on psychovegetative and hemodynamic disturbances. MATERIAL AND METHODS:Ultrasonic dopplerography of the region of common carotid artery, ECG, examinations of central hemodynamics, veget...

journal_title：Terapevticheskii arkhiv

authors： Shpak LV,Kolbasnikov SV

更新日期：2001-01-01 00:00:00

abstract：AIM:To study biochemical indicators of the hematosalivary barrier operation in varying activity of articular inflammation and their correlations. MATERIAL AND METHODS:Biochemical indices of mixed saliva and peripheral blood were studied in 38 healthy subjects and 99 patients with rheumatoid arthritis (RA). RESULTS:Op...

journal_title：Terapevticheskii arkhiv

authors： Ulanova EA,Grigor'ev IV,Novikova IA

更新日期：2001-01-01 00:00:00

abstract：AIM:To study clinical features of typhoid fever (TF) in migrants (subjects in military service in Tadjikistan). MATERIAL AND METHODS:In chronic water epidemic TF symptoms were studied in 547 young soldiers and officers serving in Tadjikistan with incomplete biological and/or professional adaptation. RESULTS:In most c...

journal_title：Terapevticheskii arkhiv

authors： Makhnev MV

更新日期：2001-01-01 00:00:00

abstract：AIM:Investigation of functional-metabolic activity of leukocytes by assessment of basic components of the microbicidal system in the course of chronic brucellosis with reference to the stage, severity, complications and concomitant diseases. MATERIAL AND METHODS:Time course of changes in myeloperoxidase, acid and alka...

journal_title：Terapevticheskii arkhiv

authors： Nagoev BS,Akhmedov DR,Saaeva NM

更新日期：2001-01-01 00:00:00

abstract：AIM:To clarify the effect of cyclosporin A (CSA) on the apoptosis and proliferative activity of bone marrow cells in patients with aplastic syndromes by trepanobiopsy evidence. MATERIALS AND METHODS:The TUNEL immunohistochemical assay was used to study apoptosis of bone marrow cells in the histological specimens from ...

journal_title：Terapevticheskii arkhiv

authors： Kokhno AV,Savchenko VG,Parovichnikova EN,Kharazishvili DI,Sokolovskaia AA,Lukashina MI,Baryshnikov AIu

更新日期：2001-01-01 00:00:00

abstract：AIM:To study basic parameters of hemostasis in the course of acute poststreptococcal glomerulonephritis (APSGN). MATERIAL AND METHODS:Platelets number and aggregation 4-platelet factor, Willebrand's factor, activated partial thromboplatelet time, antithrombin III, fibrin-monomeric complexes and products of degradation...

journal_title：Terapevticheskii arkhiv

authors： Movchan EA,Tov NL,Loskutova SA,Chuprova AV

更新日期：2001-01-01 00:00:00

abstract：AIM:To estimate cost-effect efficacy of vasaprostan treatment of inpatients with arterial chronic obliteration (ACO) with critical ischemia of the lower limbs (Fonten stage III-IV). MATERIAL AND METHODS:Case histories of 105 ACO patients with critical ischemia of the lower limbs (mean age 65 +/- 11.8 years) were analy...

journal_title：Terapevticheskii arkhiv

authors： Vorob'ev PA,Dergach EV,Gerasimov VB,Avksent'eva MV

更新日期：2001-01-01 00:00:00

abstract：AIM:To assess orthogonal ECG system McFee-Parungao in exercise test performed by patients with ischemic heart disease (IHD). MATERIAL AND METHODS:The trial included 103 patients: 41 patients with IHD, 23 patients with IHD combined with arterial hypertension and 39 control patients free of IHD. All the patients perform...

journal_title：Terapevticheskii arkhiv

authors： Komarova OA,Kotova LA,Iarnykh EV

更新日期：2001-01-01 00:00:00

abstract：AIM:To study efficiency in rheumatoid arthritis (RA) of local radiotherapy methods: radionuclide synovectomy (RS), x-ray therapy (XRT) and local gamma-therapy (LGT) proposed by the authors. MATERIAL AND METHODS:175 patients with RA received local radiotherapy on the knee joints. The patients were divided into three gr...

journal_title：Terapevticheskii arkhiv

authors： Marusenko IM,Ignat'ev VK,Zdorov AE

更新日期：2001-01-01 00:00:00

abstract：AIM:To evaluate occurrence of DNA-abzymes with catalytic (DNA-hydrolysing) and cytotoxic properties in patients with systemic lupus erythematosus (SLE) for examination of clinical value of DNA-abzymes in diagnosis of autoimmune syndrome and apoptosis level in different variants of immunopathology. MATERIAL AND METHODS...

journal_title：Terapevticheskii arkhiv

authors： Suchkov SV,Gabibov AG,Alekberova ZS,Gnuchev NV

更新日期：2001-01-01 00:00:00

abstract：AIM:To compare effectiveness of two long-acting calcium antagonists--amlodipin and diltiazem--in patients with ischemic heart disease (IHD) and stable angina of effort (SAE). MATERIAL AND METHODS:31 IHD patients with SAE entered the double blind randomized trial. The patients received either amlodipin (5-10 mg once a ...

journal_title：Terapevticheskii arkhiv

authors： Martsevich SIu,Sementsov DP,Kutishenko NP,Alimova EV

更新日期：2001-01-01 00:00:00

abstract：AIM:To study changes in left atrial volume, geometry and function in myocardial infarction (MI) patients treated with beta-adrenoblocker and ACE inhibitor. MATERIAL AND METHODS:65 patients with Q-wave myocardial infarction (MI) were followed up for 6 months. Regular check-ups included clinical examination, ECG, echo-C...

journal_title：Terapevticheskii arkhiv

authors： Mazur NA,Vikent'ev VV

更新日期：2001-01-01 00:00:00

abstract：AIM:To compare the efficacy of monotherapy with quadropril (spirapril) vs captopril in essential hypertension. MATERIAL AND METHODS:20 female patients aged 55 +/- 2 years with moderate hypertension (WHO classification) were included in the study. 16 patients had congestive heart failure stage II NYHA and 4 patients st...

journal_title：Terapevticheskii arkhiv

authors： Polimbetov DS,Kraĭsman VA,Isaeva BG,Aliev FR

更新日期：2000-01-01 00:00:00

abstract：AIM:To determine clinical efficiency and tolerance of paxil (paroxetin) in the treatment of panic disorders. MATERIAL AND METHODS:An open, non-comparative 7 week study entered 60 patients (mean age 36.6 +/- 3.22 years) with panic disorders and agoraphobias with panic disorders. Paroxetin was given in a single daily do...

journal_title：Terapevticheskii arkhiv

authors： Mosolov SN,Smulevich AB,Nuller IuL,Grigor'evskikh VS,Kostiukova EG,Kuzavkova MV,Koliutskaia EV,Andriushchenko AV,Zelenina EV,Kosinskiĭ VP,Kozlovskiĭ VL,Bykov SI,Pererva IG

更新日期：2000-01-01 00:00:00

abstract：AIM:To investigate the effect of acarbose, intestinal alpha-glucosidase inhibitor, on lipid metabolism in patients with non-insulin-dependent diabetes mellitus (NIDDM). MATERIAL AND METHODS:Glucobai was given for 6 months in a dose 300 mg/day to 63 NIDDM patients aged 40-69 years. The examination covered indices of gl...

journal_title：Terapevticheskii arkhiv

authors： Rosliakova LV,Roĭtman AP,Ametov AS,Dolgov VV

更新日期：2000-01-01 00:00:00

abstract：AIM:To study antianginal effectiveness of trimetazidine (TMS) in monotherapy and combined antianginal therapy; to design approaches to prediction of its effect. MATERIAL AND METHODS:An open cross-over randomised trial enrolled 29 anginal patients. They were given a single TMS dose (60 mg) and its effect was compared t...

journal_title：Terapevticheskii arkhiv

authors： Zhiliaev EV,Urzhumova TV,Glazunov AV,Sorokoletov SM,Dzhanashiia PKh

更新日期：2000-01-01 00:00:00

abstract：AIM:To examine clinical, immunological and morphological features of HGV- and TTV-infections in patients with chronic hepatic diseases (CHD) and assess efficiency of treatment of HGV-seropositive patients. MATERIAL AND METHODS:202 patients with CHD were examined for markers of HBV-, HCV-, HGV- and TTV-infections. Some...

journal_title：Terapevticheskii arkhiv

authors： Loginov AS,Sharafanova TI,Reshetniak VI,Il'chenko LIu,Shepeleva SD,Serova TI,Tkachev VD

更新日期：2000-01-01 00:00:00

abstract：AIM:To study types of anxious disorders (AD) in patients with rheumatoid arthritis (RA) and AD correlations with clinicolaboratory indices. MATERIAL AND METHODS:80 RA patients and 38 healthy subjects have undergone MMPI test. RESULTS:95% of the examinees were found to have AD which seem to form in active participatio...

journal_title：Terapevticheskii arkhiv

authors： Ulanova EA,Grigor'ev IV,Novikova IA

更新日期：2000-01-01 00:00:00

abstract：AIM:To study velocity characteristics of changes in the levels of insulin, glucagon and C-peptide in the course of the intravenous glucose tolerance test (IGTT). MATERIAL AND METHODS:Glucose, insulin, glucagon and peptide levels were measured in the course of IGTT performed in 50 patients with coronary atherosclerosis...

journal_title：Terapevticheskii arkhiv

authors： Denisova TP,Malinov IA

更新日期：2000-01-01 00:00:00

abstract：AIM:Assessment of leukocyte activity with spontaneous NBT-test in influenza patients regarding the disease stage, severity, complication and concomitant diseases. MATERIAL AND METHODS:107 influenza patients aged 16-84 years were studied. 70 patients had no complications, 11 patients had early influenzal pneumonia, 26 ...

journal_title：Terapevticheskii arkhiv

authors： Nagoev BS,Orazaev NG

更新日期：2000-01-01 00:00:00

abstract：AIM:To achieve a maximal complete remission rate in patients with recurrent and refractory Hodgkin's disease. To find out a group of patients in whom surgical removal of the residual mediastinal mass would be most effective. MATERIAL AND METHODS:46 patients with Hodgkin's disease received Dexa-BEAM chemotherapy follow...

journal_title：Terapevticheskii arkhiv

authors： Stroiakovskiĭ DL,Pivnik AV,Shavlokhov VS,Sotnikov VM,Moiseeva TN,Rasstrigin NA,Margolin OV,Efimov IV,Dzhumabaeva BT,Kaplanskaia IB,Roshchina LS

更新日期：2000-01-01 00:00:00

abstract：AIM:To investigate a potential of a new marker of activity of interstitial pulmonary diseases (IPD)--mucin 3EG5--in monitoring of effectiveness of the antiinflammatory therapy. MATERIALS AND METHODS:Serum mucin antigen 3EG5 (glycolyl-sialylated glycoprotein) was assessed with sandwich immunoassay constructed using a m...

journal_title：Terapevticheskii arkhiv

authors： Avdeeva OE,Lebedin IuS,Avdeev SN,Chuchalin AG

更新日期：2000-01-01 00:00:00

abstract：AIM:To study paramagnetic centers (PMC) of some biological media in cholecystitis patients. MATERIALS AND METHODS:PMC of 81 patients with chronic acalculous cholecystitis and 29 patients with acute calculous cholecystitis were examined using 3-cm radiospectrometer "Rubin" employing low-temperature fixation of biologic...

journal_title：Terapevticheskii arkhiv

authors： Saĭfutdinov RG,Shcherbakova AV

更新日期：2000-01-01 00:00:00

abstract：AIM:To try arthrotek, a combined drug, in patients with rheumatoid arthritis (RA). MATERIALS AND METHODS:10 RA women aged 30 to 60 years with endoscopically verified minimal affection of gastroduodenal mucosa (not more than 25 hemorrhages and/or 5 erosions) received arthrotek (1 tablet 3 times a day for 3 months). The...

journal_title：Terapevticheskii arkhiv

authors： Iakushin SS,Filonenko SP,Dediunina RS,Lukina IM

更新日期：2000-01-01 00:00:00

abstract：AIM:To study clinical and psychological features of patients with coronary heart disease (CHD) and their comparison with obesity. MATERIALS AND METHODS:The presence and intensity of cardialgia, Ketle's index, body mass fat component, tolerance to isometric load were determined in 104 patients with stable angina of eff...

journal_title：Terapevticheskii arkhiv

authors： Gnedov DA

更新日期：2000-01-01 00:00:00

abstract：AIM:To elucidate the effects of combined therapy with glucocorticosteroids (GCS) and recombinant human interferon alpha or gamma (IFN) on proliferative responses of T-lymphocytes activated by various surface molecules (CD3 and CD2) in patients with SLE. MATERIALS AND METHODS:A 3-month trial entered 3 groups 15 patient...

journal_title：Terapevticheskii arkhiv

authors： Stanislav ML,Balabanova RM,Nikonova MF,Litvina MM,Iarilin AA

更新日期：2000-01-01 00:00:00

abstract：AIM:To investigate the effect of recombinant alpha 2b-interferon (r alpha 2b-IFN) on functional capacity of peripheral blood (PB) T cells in rheumatoid arthritis (RA) patients and the relationship between functional characteristics of T lymphocytes and the disease activity. MATERIALS AND METHODS:PB mononuclear cells (...

journal_title：Terapevticheskii arkhiv

authors： Iarilina AA,Nikonova MF,Litvina MM,Balabanova RM,Iarilin AA

更新日期：2000-01-01 00:00:00

abstract：AIM:To characterize elimination of some enzymes in intermittent hemofiltration (HF) in patients with acute renal failure (ARF). MATERIAL AND METHODS:22 patients with oliguric ARF have undergone 52 procedures of intermittent HF. Before the procedure and after it the activity of enzymes (AA, AP, ACE, LAP, GGT, GDG, AlAT...

journal_title：Terapevticheskii arkhiv

authors： Timokhov VS,Kazakov IV,Selezneva SN,Komissarova IV,Smirnova LM

更新日期：2000-01-01 00:00:00

abstract：AIM:To evaluate uric acid (UA) levels in patients with postinfarction chronic cardiac failure (CCF) and to investigate correlation between accumulation of uric acid, CCF severity and some other parameters. MATERIAL AND METHODS:UA levels were determined with enzyme immunoassay and acid-base status of capillary and veno...

journal_title：Terapevticheskii arkhiv

authors： Tereshchenko SN,Levchuk NN,Drozdov VN,Moiseev VS

更新日期：2000-01-01 00:00:00